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Articles from Thomas Schmitt | Selfgrowth.com
- Research Progress of Pectin and Its Medical Application - by Submitted on May 28, 2023 from Thomas SchmittPectin is a hydrophilic vegetable gum. Widely present in the fruits, roots, stems and leaves of higher plants, it is a component of the cell wall. The pectin ontent of different plants or different parts of the same plant varies greatly. So far, only a few plants with high pectin content have ...
Views: 5 - How Do You Test Staphylococcus aureus? - by Submitted on May 28, 2023 from Thomas SchmittStaphylococcus aureus is an important pathogen causing suppurative infection in humans and animals, and it is also one of the common pathogens causing human food poisoning. Staphylococcus aureus is widely distributed in nature, such as air, soil, water, and other environments. This bacteria is ...
Views: 5 - Calprotectin in Inflammatory Diseases - by Submitted on May 28, 2023 from Thomas SchmittInflammation is an important defense response of the body that can control and clear various endogenous or exogenous damaging factors acting on the body, and also has a role in repairing damage. However, excessive or persistent inflammation can also cause damage to tissues and organs. ...
Views: 5 - What is Antibody-Dependent Enhancement - by Submitted on May 28, 2023 from Thomas SchmittAfter the host is infected by the virus, the immune system can generate a corresponding immune response. Antibodies specific to viral surface proteins produced at this time can often prevent the virus from adhering to the surface of host cells, making it incapable of infecting cells. However, in ...
Views: 5 - Carrageenans as a Versatile Tool in Drug Delivery - by Submitted on May 08, 2023 from Thomas SchmittDrug delivery is the process of administering pharmaceutical substances to targeted areas in the body. It plays a vital role in the effective treatment of various diseases. However, drug delivery is often challenged by the body’s natural defenses, such as the gastrointestinal tract and the ...
Views: 22 - What Are Polyethylenimine Magnetic Particles? - by Submitted on May 08, 2023 from Thomas SchmittPolyethylenimine (PEI) is a cationic polymer that contains repeating units composed of an amine group and a CH2CH2 spacer. Notably, PEI is an organic polymer that has the highest positive charge density potential as every third atom of this polymer is a protonable amino nitrogen. Two forms of ...
Views: 20 - Antibody-Immunoglobulin - by Submitted on May 08, 2023 from Thomas SchmittAntibody, also called Immunoglobulin, is a large Y globulin secreted by Effector B cell which is used in identifying and neutralizing the outsiders like bacterial and virus. Antibody is only found in blood ,body fluid and cytomembrane’s surface of Vertebrate. In addition, antiboy can identify ...
Views: 23 - What are AMOTs? - by Submitted on May 08, 2023 from Thomas SchmittAMOT family, also known as the Motin family, has three members: angiomotin (AMOT), angiomotin-like protein 1 (AMOTL1), and angiomotin-like protein 2 (AMOTL2). There are two shear isomers of AMOT, AMOT-P130 and AMOT-P80. AMOT was first discovered and named in 2001. Existing studies have shown ...
Views: 20 - What Are Phosphate Magnetic Particles? - by Submitted on Apr 03, 2023 from Thomas SchmittPhosphonates or phosphonic acids are organic compounds containing C–PO(OH)2 or C–PO(OR)2 groups (where R = alkyl, aryl). Most phosphonates are highly water-soluble, while phosphonic acids are only sparingly soluble. Phosphonates are not volatile and are poorly soluble in organic solvents. ...
Views: 39 - A Review of Proteolytic Targeting Chimeras - by Submitted on Apr 03, 2023 from Thomas SchmittThe concept of proteolytic targeting chimera (PROTAC) was first proposed by Crews and Deshaies laboratory in 2001, the team successfully achieved the degradation of methionyl aminopeptidase 2 (MetAp-2) by PROTAC method. Since then, PROTACs targeting androgen receptor (AR) and estrogen receptor ...
Views: 36 - Study on Partial Glycoprotein of Feline Herpesvirus Type 1 - by Submitted on Apr 03, 2023 from Thomas SchmittFeline herpesvirus type 1 (FHV-1) can cause acute and highly contagious infectious diseases in cats, namely feline infectious rhinotracheitis. In 1958, FHV-1 was isolated and identified for the first time from kittens suffering from respiratory diseases in the United States by Crandell et al. ...
Views: 38 - Influenza A: Unraveling the Mystery of H1N1 and H3N2 - by Submitted on Apr 03, 2023 from Thomas SchmittInfluenza A viruses, the culprits of respiratory illness in humans, are a complex and multifaceted group of viruses. Among the numerous subtypes of Influenza A, H1N1 and H3N2 with a notorious history of causing seasonal epidemics and pandemics, demand special attention. Influenza A H1N1, also ...
Views: 41 - A Non-invasive Test for Detecting and Locating Cancer Cells - by Submitted on Mar 03, 2023 from Thomas SchmittWhen diagnosing cancer, most of the tests used by doctors (such as mammography, colonoscopy, and CT scans) are based on imaging. Engineers at the Massachusetts Institute of Technology have now created new diagnostic nanoparticles that can be used to monitor tumor recurrence after treatment or to ...
Views: 48 - Gene Carrier Based on Nanomaterials - by Submitted on Mar 03, 2023 from Thomas SchmittGene therapy refers to the introduction of normal foreign genes into target cells to compensate or correct diseases caused by gene defects or abnormalities, so as to achieve the purpose of treatment. Naked DNA usually requires physical methods to enter tissues or cells, and DNA is easily ...
Views: 55 - Detection of Impurities Related to Biopharmaceutical Processes - by Submitted on Mar 03, 2023 from Thomas SchmittBiopharmaceutical impurities can be divided into two categories: extraneous contaminants and product-related impurities. Extraneous contaminants include microbial contamination, pyrogens, cellular components, components in culture media, substances from various steps in the production process, ...
Views: 51 - Transglutaminases in Medical Research - by Submitted on Mar 03, 2023 from Thomas SchmittTransglutaminase (TGase) is an enzyme that catalyzes the acyl transfer reaction. It uses the C-carboxamide group of the glutamine residue in the peptide bond as the acyl donor, and the E-amino group of the lysyl residue in the polypeptide chain as the acyl acceptor, forming intramolecular and ...
Views: 58 - Introduction of Chitosan as Nano-drug Delivery Carrier - by Submitted on Feb 01, 2023 from Thomas SchmittChitin is the second largest natural polymer after cellulose, and it exists widely in nature, such as shells of crustaceans such as shrimps, crabs, insects, and cell walls of fungi. Although chitin has good biocompatibility and biodegradability, its poor solubility limits its practicality in the ...
Views: 50 - What Are Melamine Resin Particles? - by Submitted on Feb 01, 2023 from Thomas SchmittMelamine (1, 3, 5-triamino-2, 4, 6-triazine) resin, or melamine formaldehyde (MF) is one of the hardest and stiffest thermosetting polymers, which provides good properties and performance. It is an amino resin and has various material advantages, such as transparency, better hardness, thermal ...
Views: 53 - Cancer Target: Mesothelin - by Submitted on Feb 01, 2023 from Thomas SchmittMesothelin is a glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein. Its biological function has not yet been clarified, but due to its limited distribution in normal tissues and high expression in some tumor tissues, it is expected to be used in tumor-specific treatment. In ...
Views: 62 - Breakthrough Ideas for Parkinson’s Disease Treatment - by Submitted on Feb 01, 2023 from Thomas SchmittParkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by bilateral motor (eg, bradykinesia, resting tremor, postural instability, rigidity) and nonmotor (eg, memory loss, depression) disability. About 10 million people worldwide suffer from Parkinson’s disease. ...
Views: 57 - Gene Structure and Function of Porcine Pseudorabies Virus - by Submitted on Dec 27, 2022 from Thomas SchmittPorcine pseudorabies (PR) is an acute infectious disease of pigs caused by porcine pseudorabies virus (PRV). PRV belongs to the herpesviridae family, the alphaherpesviridae subfamily, and the genus porcine herpesvirus, which is a linear DNA virus. PRV can cause vomiting, high fever and ...
Views: 73 - Research Status of Virus Vaccines - by Submitted on Dec 27, 2022 from Thomas SchmittSince the discovery of cowpox inoculation to prevent smallpox in the 18th century, vaccines have become an important means for human beings to resist pathogen infection and prevent the occurrence of diseases. Although immunization has eliminated or controlled the spread and pathogenic hazards of ...
Views: 69 - Research Progress of PROTAC in the Treatment of Malignant Tumors - by Submitted on Dec 27, 2022 from Thomas SchmittMalignant tumors are a major global public health problem, the leading cause of death in developing countries and the second leading cause of death in developed countries. Traditional treatment methods such as surgical resection, radiotherapy and chemotherapy have serious side effects on the ...
Views: 77 - What Are Gold NanoCages? - by Submitted on Dec 27, 2022 from Thomas SchmittGold nanocages refer to the hollow gold nanostructures with porous walls that were developed by Sun and Xia and Chen et al. in the early 2000s. The hollow and porous structures are synthesized by the galvanic replacement between silver nanocubes and chloroauric acid in aqueous solution. By ...
Views: 81 - What Is Nucleic Acid Extraction? - by Submitted on Nov 29, 2022 from Thomas SchmittNucleic acid is the main material for storing, copying, and transmitting genetic information. Nucleic acid extraction is one of the most fundamental steps in molecular biology applications and is a prerequisite for many experiments. The quality of extracted nucleic acid will directly affect the ...
Views: 82 - Advantages of Liposomal in Drug Delivery - by Submitted on Nov 29, 2022 from Thomas SchmittLiposomes are ultra-micro spherical carrier preparations formed by lipid bilayers, and are typical representatives of nano-drug delivery systems. When amphiphilic molecules such as phospholipids are dispersed in the aqueous phase, the hydrophobic tails of the molecules gather together, and the ...
Views: 78 - The Return of Bird Flu - by Submitted on Nov 28, 2022 from Thomas SchmittAccording to data from the European Food Safety Authority, the European Centre for Disease Prevention and Control and the EU Avian Influenza Reference Laboratory, large-scale bird flu has occurred in Europe since June in 2022, affecting 37 European countries, from Norway to Sri Lanka. The Valbar ...
Views: 83 - A Brief Description of Porcine Reproductive and Respiratory Syndrome Virus - by Submitted on Nov 28, 2022 from Thomas SchmittPorcine Reproductive and Respiratory Syndrome Virus (PRRSV) belongs to the Arteriviridae family and belongs to the Arterivirus. PRRSV can be divided into type I (PRRSV type I) and type II (PRRSV type II). The main clinical symptoms are abortion, stillbirth and mummified fetus of pregnant sows, ...
Views: 67 - What Are Iron Oxide Nanoparticles? - by Submitted on Oct 31, 2022 from Thomas SchmittIron oxides are common compounds, which are widespread in nature and can be readily synthesized in the laboratory. Iron oxide nanoparticles (NPs) typically refer to the materials that consist of magnetite (Fe3O4) or maghemite (γ-Fe2O3) and have a size ranging from 1 to 100 nm. These ...
Views: 83 - The Function of Drug Coating - by Submitted on Oct 31, 2022 from Thomas SchmittCoating refers to the unit operation of applying a layer of outer coating material to the dry surface of the formulation. This coating material not only makes the product easier to identify, but even improves the pharmacokinetic properties of the drug by altering its release: ensuring that the ...
Views: 103 - African Swine Fever Virus Detection Method - by Submitted on Oct 31, 2022 from Thomas SchmittAfrican swine fever(ASF) is a contagious infectious disease caused by African swine fever virus (ASFV) that spreads only among domestic pigs and wild boars, with a rapid onset, short course of disease, and a fatality rate of 100%. This article summarizes the latest progress in the detection ...
Views: 83 - Overview of Brucella Abortus - by Submitted on Oct 31, 2022 from Thomas SchmittBrucellosis is a zoonotic infectious disease caused by Brucella, and it is one of the most widespread zoonotic diseases in the world, which brings great losses to the animal husbandry industry. Here, we will outline several aspects about the pathogen, living environment, identification, and ...
Views: 83 - What are Biopolymers? - by Submitted on Sep 27, 2022 from Thomas SchmittBiodegradable polymers are most often referred to as “biopolymers” because most of these polymers are derived from various natural sources. There are few in the list of biodegradable biopolymers in nature. PLA, PHA and starch are the most commonly used biopolymers that have minimal or minimal ...
Views: 109 - How to Know Ultrasound Imaging Contrast Agents in 5 Minutes? - by Submitted on Sep 27, 2022 from Thomas SchmittUltrasound imaging is a well-established clinical imaging technique that provides real-time, quantitative anatomical and physiological information about the human body. It uses high-frequency sound waves to look inside the body, and as ultrasound images are captured in real-time, they can also ...
Views: 93 - Introduction to Measles Virus - by Submitted on Sep 27, 2022 from Thomas SchmittMeasles virus (MV) is the causative agent of measles in children. Measles is a highly contagious infectious disease. According to the World Health Organization, about 20 million children worldwide suffer from measles every year. Measles virus is highly contagious and has high morbidity. In ...
Views: 101 - Legionella Pathogenicity Detection Method - by Submitted on Sep 27, 2022 from Thomas SchmittLegionnaires’ disease (LD) first broke out on a large scale at a military rally in Philadelphia in 1976, killing 34 people. Since then, there have been outbreaks or sporadic transmission of Legionnaires’ disease in the community, in hospitals, and in travel. Legionella is a facultative ...
Views: 99 - Metal-organic Frameworks and Novel Drug-Carrying Systems - by Submitted on Aug 24, 2022 from Thomas SchmittMetal-organic frameworks (MOFs) form long-range ordered geometric structures through the coordination and binding of metal ions and small organic molecules, changing metal elements and small organic molecules, resulting in an ever-expanding family of MOFs. Due to their excellent properties such ...
Views: 104 - What Are Contrast Agents for Computed Tomography? - by Submitted on Aug 24, 2022 from Thomas SchmittComputed tomography, or CT, was developed in 1960s and early 1970s. It refers to a computerized X-ray imaging procedure in which a narrow beam of X-rays is aimed at the patient and rapidly revolves around the body, producing signals that are processed by a machine computer to generate a ...
Views: 114 - Introduction of Complement Component 5 Receptor - by Submitted on Aug 24, 2022 from Thomas SchmittThe complement system is considered to be a biological effector system composed of a group of thermolabile enzymatically active globulins on the surface of serum, tissue fluid and cell membrane. The membrane attack complex is finally formed by a complex enzymatic cascade reaction, which realizes ...
Views: 101 - Overview of Monkeypox - by Submitted on Aug 24, 2022 from Thomas SchmittMonkeypox is caused by the monkeypox virus. Monkeypox virus is a virus belonging to the genus Orthopoxvirus of the Poxviridae family. Monkeypox virus has the typical shape of Orthopox virus, with a rounded brick shape or an oval shape and a size of 200-400 nm. The virus is enveloped by a ...
Views: 96 - The Life Cycle of Epstein-Barr Virus - by Submitted on Jul 20, 2022 from Thomas SchmittEpstein-Barr Virus (EBV) is a large enveloped virus of double-stranded DNA among the eight known herpesviruses. After EBV infection of cells, it accumulates in the nucleus, and there are two life cycles, with alternating phases of latency and lysis. EBV infection is associated with a variety of ...
Views: 102 - The Life Cycle of Epstein-Barr Virus - by Submitted on Jul 20, 2022 from Thomas SchmittEpstein-Barr Virus (EBV) is a large enveloped virus of double-stranded DNA among the eight known herpesviruses. After EBV infection of cells, it accumulates in the nucleus, and there are two life cycles, with alternating phases of latency and lysis. EBV infection is associated with a variety of ...
Views: 116 - Mechanism of EBV to Invade Host Cells - by Submitted on Jul 20, 2022 from Thomas SchmittEpstein-Barr virus (EBV) is a kind of γ-herpes virus that is infected with human beings. In 1964, the Epstein team found in Burkittlymphoma (BL) that it consists of a double-chain DNA of 184 KB, mainly through saliva spread. 95%of the world’s people have been infected with EBV, which can be ...
Views: 117 - Polyacrylate Nanoparticles You Don’t Want to Miss - by Submitted on Jul 20, 2022 from Thomas SchmittWhat are polyacrylates nanoparticles? Polyacrylates are an important class of soft, tough and rubbery polymers, which are known for their high transparency, good impact toughness and elasticity. Polyacrylates and their copolymers are one of the polymeric nanoparticles (NPs). Polymeric ...
Views: 104 - Sucrose Polymer Overview - by Submitted on Jul 20, 2022 from Thomas SchmittSucrose is a disaccharide with a unique structure. It is a non-reducing sugar formed by removing a molecule of water from the glycoside hydroxyl group of a molecule of α-D-(+)-glucopyranose and a molecule of β-D-(-)-fructofuranose. During the hydrolysis process, the specific optical rotation of ...
Views: 110 - What Are D-Glucosamines? - by Submitted on Jun 13, 2022 from Thomas SchmittGlucosamine is a natural component of cartilage and is widely used as an over-the-counter nutritional supplement to reduce the pain and cartilage loss of osteoarthritis. Glucosamine is usually taken in combination with chondroitin, which is a glycosaminoglycan that also exists in ...
Views: 147 - What Are NanoPlates? - by Submitted on Jun 13, 2022 from Thomas SchmittNanoplates are classified as having only one dimension in the nanometre range. The most widely utilized types of nanoplates are silicate clay minerals (montmorillonite) and graphite, which both exist in the form of layered materials. The main advantage of layered nanomaterials is their ...
Views: 153 - Staphylococcus aureus Enterotoxin B - by Submitted on Jun 13, 2022 from Thomas SchmittStaphylococcus aureus (S. aureus) is an important food-borne pathogen that causes food contamination and food poisoning. It is also a symbiont of human skin and mucous membranes. About 20% to 30% of healthy individuals carry Staphylococcus aureus. Animal foods are susceptible to Staphylococcus ...
Views: 175 - Study on Recombinant Hirudin - by Submitted on Jun 13, 2022 from Thomas SchmittAlthough natural hirudin is in great demand in clinical and pharmaceutical research, it is not easy to obtain. With the gradual exhaustion of natural leech resources, the gap between supply and demand is expanding year by year. In order to alleviate the shortage of leech resources, researchers ...
Views: 128 - What Are D-Glucosamines? - by Submitted on May 24, 2022 from Thomas SchmittGlucosamine is a natural component of cartilage and is widely used as an over-the-counter nutritional supplement to reduce the pain and cartilage loss of osteoarthritis. Glucosamine is usually taken in combination with chondroitin, which is a glycosaminoglycan that also exists in ...
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