Brucellosis is a zoonotic infectious disease caused by Brucella, and it is one of the most widespread zoonotic diseases in the world, which brings great losses to the animal husbandry industry. Here, we will outline several aspects about the pathogen, living environment, identification, and ... Views: 300
Biodegradable polymers are most often referred to as “biopolymers” because most of these polymers are derived from various natural sources. There are few in the list of biodegradable biopolymers in nature. PLA, PHA and starch are the most commonly used biopolymers that have minimal or minimal ... Views: 361
Ultrasound imaging is a well-established clinical imaging technique that provides real-time, quantitative anatomical and physiological information about the human body. It uses high-frequency sound waves to look inside the body, and as ultrasound images are captured in real-time, they can also ... Views: 279
Measles virus (MV) is the causative agent of measles in children. Measles is a highly contagious infectious disease. According to the World Health Organization, about 20 million children worldwide suffer from measles every year. Measles virus is highly contagious and has high morbidity. In ... Views: 293
Legionnaires’ disease (LD) first broke out on a large scale at a military rally in Philadelphia in 1976, killing 34 people. Since then, there have been outbreaks or sporadic transmission of Legionnaires’ disease in the community, in hospitals, and in travel. Legionella is a facultative ... Views: 262
Metal-organic frameworks (MOFs) form long-range ordered geometric structures through the coordination and binding of metal ions and small organic molecules, changing metal elements and small organic molecules, resulting in an ever-expanding family of MOFs. Due to their excellent properties such ... Views: 301
Computed tomography, or CT, was developed in 1960s and early 1970s. It refers to a computerized X-ray imaging procedure in which a narrow beam of X-rays is aimed at the patient and rapidly revolves around the body, producing signals that are processed by a machine computer to generate a ... Views: 317
The complement system is considered to be a biological effector system composed of a group of thermolabile enzymatically active globulins on the surface of serum, tissue fluid and cell membrane. The membrane attack complex is finally formed by a complex enzymatic cascade reaction, which realizes ... Views: 272
Monkeypox is caused by the monkeypox virus. Monkeypox virus is a virus belonging to the genus Orthopoxvirus of the Poxviridae family. Monkeypox virus has the typical shape of Orthopox virus, with a rounded brick shape or an oval shape and a size of 200-400 nm. The virus is enveloped by a ... Views: 317
Epstein-Barr Virus (EBV) is a large enveloped virus of double-stranded DNA among the eight known herpesviruses. After EBV infection of cells, it accumulates in the nucleus, and there are two life cycles, with alternating phases of latency and lysis. EBV infection is associated with a variety of ... Views: 248
Epstein-Barr Virus (EBV) is a large enveloped virus of double-stranded DNA among the eight known herpesviruses. After EBV infection of cells, it accumulates in the nucleus, and there are two life cycles, with alternating phases of latency and lysis. EBV infection is associated with a variety of ... Views: 292
Epstein-Barr virus (EBV) is a kind of γ-herpes virus that is infected with human beings. In 1964, the Epstein team found in Burkittlymphoma (BL) that it consists of a double-chain DNA of 184 KB, mainly through saliva spread. 95%of the world’s people have been infected with EBV, which can be ... Views: 289
What are polyacrylates nanoparticles?
Polyacrylates are an important class of soft, tough and rubbery polymers, which are known for their high transparency, good impact toughness and elasticity. Polyacrylates and their copolymers are one of the polymeric nanoparticles (NPs).
Polymeric ... Views: 240
Sucrose is a disaccharide with a unique structure. It is a non-reducing sugar formed by removing a molecule of water from the glycoside hydroxyl group of a molecule of α-D-(+)-glucopyranose and a molecule of β-D-(-)-fructofuranose. During the hydrolysis process, the specific optical rotation of ... Views: 315
Glucosamine is a natural component of cartilage and is widely used as an over-the-counter nutritional supplement to reduce the pain and cartilage loss of osteoarthritis. Glucosamine is usually taken in combination with chondroitin, which is a glycosaminoglycan that also exists in ... Views: 347
Nanoplates are classified as having only one dimension in the nanometre range. The most widely utilized types of nanoplates are silicate clay minerals (montmorillonite) and graphite, which both exist in the form of layered materials. The main advantage of layered nanomaterials is their ... Views: 397
Staphylococcus aureus (S. aureus) is an important food-borne pathogen that causes food contamination and food poisoning. It is also a symbiont of human skin and mucous membranes. About 20% to 30% of healthy individuals carry Staphylococcus aureus. Animal foods are susceptible to Staphylococcus ... Views: 368
Although natural hirudin is in great demand in clinical and pharmaceutical research, it is not easy to obtain. With the gradual exhaustion of natural leech resources, the gap between supply and demand is expanding year by year. In order to alleviate the shortage of leech resources, researchers ... Views: 297
Glucosamine is a natural component of cartilage and is widely used as an over-the-counter nutritional supplement to reduce the pain and cartilage loss of osteoarthritis. Glucosamine is usually taken in combination with chondroitin, which is a glycosaminoglycan that also exists in ... Views: 333
Melamine (1, 3, 5-triamino-2, 4, 6-triazine) resin, or melamine formaldehyde (MF) is one of the hardest and stiffest thermosetting polymers, which provides good properties and performance. It is an amino resin and has various material advantages, such as transparency, better hardness, thermal ... Views: 361
An international team of researchers has discovered the first human antibody that effectively neutralizes two types of hantaviruses in animal models, according to a study published online in the journal Science Translational Medicine. Based on their preliminary results, the antibody appears to ... Views: 264
Strongyloides is an opportunistic pathogenic parasitic nematode. Adults parasitize in the small intestine of cats, dogs and humans. The larvae can invade lung, brain, liver, kidney and other tissues and organs, causing strongyloidiasis. The disease is mainly prevalent in warm and humid tropical ... Views: 334
Quantum dots (QDs) are semiconductor nanoparticles which exhibit size and composition-dependent optical and electronic (optoelectronic) properties. QDs are ultrasmall, typically falling in the size range between 1.5 and 10.0 nm. QDs are new types of fluorescent materials for biological labeling. ... Views: 276
Heparin, also known as standard heparin or unfractionated heparin, is a linear polysaccharide consisting of 1-4 linked disaccharide repeat units of uronic acid and glucosamine residues. Heparin was discovered nearly 100 years ago and has been used clinically as a blood anticoagulant since 1935. ... Views: 285
Over the past few decades, there have been multiple outbreaks of viruses causing severe and severe disease around the world, including known and unknown viral pathogens such as SARS-CoV, Ebola, Lassa fever, Marburg virus, Nipah virus, Hendra virus, Rift Valley fever virus and Middle East ... Views: 321
Food allergy (food hypersensitivity) is an abnormal reaction of the body’s immune system caused by food. More precisely, it is an allergic reaction caused by allergens in food.
Food allergy has become a global public health problem. According to reports, the incidence of allergic reactions in ... Views: 285
Titanium dioxide (TiO2) semiconductor nanoparticles are one kind of important and promising photocatalysts in photocatalysis because of their unique optical and electronic properties. Their properties, which are determined by the preparation method, are very crucial in photocatalysis.
What ... Views: 288
Due to the excellent characteristics of metal nanoclusters, they have many applications in the field of biomedicine. Current research shows that metal nanoclusters have good application value in biosensors, nucleic acid and protein molecular detection.
Application of Metal Nanoclusters in ... Views: 237
Hirudin is one of the most significant and most studied active ingredients in leeches and their salivary glands. It is a small molecule protein (polypeptide). Leeches are rich in hirudin, which has a strong inhibitory effect on thrombin and is the strongest natural specific inhibitor of thrombin ... Views: 315
Obesity refers to a certain degree of obvious overweight and thick fat layer, which is a state caused by excessive accumulation of body fat, especially triglycerides. Excessive food intake or changes in the body’s metabolism lead to excessive accumulation of fat in the body, resulting in ... Views: 337
Carbon dots, also known as carbon quantum dots (CQDs, CDs, or C-dots) or graphene quantum dots, possess chemical structure and physical properties similar to those of graphene oxide. Carbon quantum dots were accidentally discovered during purification of single-wall nanotubes in 2004 and have ... Views: 276
Dextran is a polysaccharide comprised of d-glucopyranose (d-glucose) repeating units linked through glycosidic linkages. It is biocompatible, biodegradable, and presents antithrombotic and anti-inflammatory properties. Dextran functional hydroxyl (–OH) groups offer an easy point for chemical ... Views: 326
The chemical structure of polyethylene glycol (PEG) is HO-(CH2CH2)n-OH, which is a general term for ethylene glycol polymers with a relative molecular mass of 200 to 8000 and above.
Polyethylene glycol is the polymer with the lowest level of absorption by proteins and cells among the known ... Views: 331
Impurities derived from cell culture include but are not limited to inducers, antibiotics, serum and other media components. These impurities need to be tested and evaluated one by one using risk assessment and risk management methods. If there is a potential impact on product safety, the ... Views: 376
Metal nanoclusters are a kind of nanomaterials with a size of less than 2 nm and stacked by 1 to 150 metal atoms. Metal nanoclusters have a typical core-shell structure, consisting of a metal atomic core and a ligand molecular shell. Ligands are usually substances that have strong covalent ... Views: 316
According to a new study published in December, small, unique antibody-like proteins called VNARs—from the shark’s immune system—can prevent the virus SARS-CoV-2 that causes COVID-19, its variants, and related coronaviruses from infecting human cells. This work is published in Nature ... Views: 286
Recently, some experts have identified an essential part of the long-term memory of the immune system, providing useful new details for the design of better vaccines that are suitable for many diseases from COVID-19 to malaria. This new study, published in the Journal of Experimental Medicine, ... Views: 304
What Are Neutral Lipids?
Neutral lipids are defined as hydrophobic molecules lacking charged groups. Neutral lipids, such as cholesteryl ester (CE), triacylglycerol (TAG), and wax ester (WE), provide organisms with inert forms of energy used in conditions of nutrient deprivation and ... Views: 306
Gold nanorods, as a kind of capsule-like gold nanoparticles with a scale from a few nanometers to hundreds of nanometers, have more peculiar optical properties than spherical gold nanoparticles due to their localized surface plasmon resonance (LSPR) effect. Gold nanorods are biomaterials ... Views: 325
The development of agricultural industrialization makes the production of agricultural products increasingly dependent on foreign substances such as pesticides, antibiotics and hormones. According to the World Health Organization (WHO), more than 1,000 pesticides are used all over the world. ... Views: 379
What is near-infrared fluorescence imaging?
Near-infrared (NIR) fluorescence is a light wavelength of 650–950 nm and is generally preferred for in vivo fluorescence imaging because of its good tissue penetration and low autofluorescence from 676565adjacent tissues. NIR fluorescence imaging is ... Views: 367
At present, a variety of chemical drugs are combined with nano-carriers to make lung-inhaled nano-preparations, and have achieved good results, such as anti-tuberculosis drugs, itraconazole, terbutaline sulfate, ciprofloxacin, curcumin and Camptothecin.
Anti-tuberculosis drugs
Polylactic ... Views: 335
One of the characteristics that cancer cells can obtain and maintain in the body is their ability to evade detection and destruction by the human immune system. For example, some tumor cells produce higher-than-normal amounts of protein as a “don’t eat me” signal, which exists on the cell ... Views: 317
Nanoparticle synthesis refers to methods for creating nanoparticles. Nanoparticles can be derived from larger molecules, or synthesized by ‘bottom-up’ methods that, for example, nucleate and grow particles from fine molecular distributions in liquid or vapour phase. Synthesis can also include ... Views: 360
Liposomes are vesicular structures, and the unique advantages imparted by lipid vesicles are their diverse range of morphologies, compositions, abilities to envelope and protect many types of therapeutic biomolecules, lack of immunogenic response, low cost, and their differential release ... Views: 385
Sphingolipids are the most structurally diverse class of membrane lipids, being composed of over 70 long-chain (sphingoid) bases, dozens of amide-linked fatty acids, and more than 300 headgroups. Sphingolipids are present in all eukaryotic and some prokaryotic organisms.
1.What Is The ... Views: 404
As we all know, tumor tissue is not only composed of cancer cells, it also contains other types of cells. These other cell types can affect tumor behavior and have a profound impact on whether the tumor will respond to therapy, including immunity therapy etc. Fibroblasts are distributed ... Views: 303
lock copolymer micelles are generally formed by the self-assembly of either amphiphilic or oppositely charged copolymers in aqueous medium. The hydrophilic and hydrophobic blocks form the corona and the core of the micelles, respectively.
Block copolymer micellescan be classified according to ... Views: 414
Monomers are molecules that can react together with other monomer molecules to form a larger polymer chain or three-dimensional network in a process called polymerization. There are mainly four types of monomers, including sugars, amino acids, fatty acids, and nucleotides, and each of these ... Views: 508