Unexplained infertility is a condition refers to a diagnosis made in those couple whose standard investigations along with tests of ovulation, semen analysis, and tubal patency are supposed to be normal. Unexplained fertility has been suggested as sustainable because conditions like tubal infertility, endometriosis, immunological infertility, and premature ovarian ageing tend to be misdiagnosed as unexplained infertility.

Unexplained Infertility Causes

There can be different causes of unexplained infertility like endometriosis. It has been said that women having endometriosis were reported to have fewer positive outcomes as compared to those women consisting of the same age without the disease. Patients facing endometriosis typically contain fewer eggs during retrieval. Along with that, lower implantation, egg quality, and pregnancy rates may also be discovered. Even fallopian tubes of those women who are facing endometriosis may function abnormally. Their ovarian function can be adversely affected and there can be a release of toxic substances by endometriosis that can harm embryos along with their implantation capacity.

Another cause is a tubal disease which is linked to a high rate of misdiagnoses. Out of which, many of the misdiagnoses can be featured to the restrictions of hysterosalpingography, that is the main screening technique implemented all over the world to diagnose tubal disease. The third cause can be premature ovarian aging. A woman is born with about 3, 00,000 follicles. The amount cuts off to near about half in every 10 years. When they pass the age of more than 37, roughly 25,000 are left. From that stage, declinations in fertility speed up in parallel with accelerated follicular loss until menopause develops at the average age of 51.

Unexplained Infertility Diagnosis

Typically, when a woman is getting unable to get pregnant even after attempting for about one complete year, this can create mental pressure, like stress can take place and several other things appear in her mind. At such cases, one may advance towards fertility testing that will provide the cause behind the problem and an idea will be taken about what to do next. However, there are lots of treatments regarding this issue but implementing some changes in life can also help a woman a lot. Like, to improve fertility on a natural basis, it is better to lose weight if been overweight, moving towards regular exercise, quit smoking, consumption of alcohol and caffeinated drinks. Such things don't harm you at all. Instead, they will provide a healthier life.

Unexplained Infertility Treatment

A range of treatment is there to explore regarding unexplained infertility like acupuncture. It is helpful in improving ovarian function and uplifting rich blood flow to the endometrium lining. Even many couples have moved towards this treatment to help them conceive. Along with that, studies have also stated about the effectiveness of some fertility treatments when they are applied in conjunction with acupuncture. Though there are medical problems like blocked tubes that can't be assisted by acupuncture.

Another method is intrauterine insemination, particularly known as IUI or artificial insemination that injects specially washed sperm to the uterus directly at the exact timing of ovulation. It eventually increases the chances of successful fertilization by getting the best quantity and quality sperm directly where it requires being.

One of the advanced technologies helpful in treating unexplained infertility is IVF. It contains egg retrieval, fertilizing the egg with the sperm and then transferring the resulting embryo(s) back into the uterus. There is a zygote intra-fallopian transfer, short-named as ZIFT, where fertilization happens in a lab but embryos get placed in the fallopian tubes instead of the uterus.

Intracytoplasmic sperm injection is yet another treatment commonly used with in-vitro fertilization. At the time of ICSI, a sperm gets injected into a mature egg and then the embryo gets transferred into the uterus.

Sometimes fertility drugs are also implemented by the doctors to induce ovulation. But there is a downside of such medications as they can increase the chances for a couple to have twins or multiples. Some fertility drugs can also be used in conjunction with assisted reproductive technology or intrauterine insemination. One more way to treat unexplained infertility is gamete intra-fallopian transfer where both sperm and eggs are placed and then fertilized inside the fallopian tubes.


At the time of dealing with any type of treatment, it is very important to consult honestly with the physician about the treatment options you may need to explore. It is because people sometimes don't want such things which are applied to them or they do not have such permits. That's why try to remember that knowledge is power.

Author's Bio: 

Indira IVF is one of the top leading Unexplained Infertility Diagnosed Centre in India. We provide Advanced Techniques Like IVF, IUI, ICSI and LAH.