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Articles from Thomas Schmitt | Selfgrowth.com
- EXO-CD24 and the Treatment of COVID-19 - by Submitted on Dec 01, 2021 from Thomas SchmittOne of the characteristics that cancer cells can obtain and maintain in the body is their ability to evade detection and destruction by the human immune system. For example, some tumor cells produce higher-than-normal amounts of protein as a “don’t eat me” signal, which exists on the cell ...
Views: 348 - Experts Find New Details about How Immune System Builds Long-term Memory - by Submitted on Jan 05, 2022 from Thomas SchmittRecently, some experts have identified an essential part of the long-term memory of the immune system, providing useful new details for the design of better vaccines that are suitable for many diseases from COVID-19 to malaria. This new study, published in the Journal of Experimental Medicine, ...
Views: 333 - Exploring Dyed Polystyrene Latex Particles Enhancing Immunoassays and Beyond - by Submitted on Mar 27, 2024 from Thomas SchmittWhat are Dyed Polystyrene Latex Particles? Polystyrene particles (PSP) are commercially available in different sizes, ranging from 15 nanometers to several micrometers, with narrow size distributions and various surface chemistries. Additionally, polystyrene is generally considered inert and ...
Views: 271 - Food Allergen Sensitization Assessment Method-In Vivo Measurement - by Submitted on Apr 15, 2022 from Thomas SchmittFood allergy (food hypersensitivity) is an abnormal reaction of the body’s immune system caused by food. More precisely, it is an allergic reaction caused by allergens in food. Food allergy has become a global public health problem. According to reports, the incidence of allergic reactions in ...
Views: 303 - Future Tumor Hemorrhage Therapy - by Submitted on Aug 08, 2019 from Thomas SchmittThe rapid proliferation of tumor cells requires a large amount of nutrients, which requires the formation of new blood vessels in the tumor environment to meet this need. Humans discovered that tumor blood vessels expanded and grew rapidly in around a hundred years ago. Later, the dependence ...
Views: 571 - Gene Carrier Based on Nanomaterials - by Submitted on Mar 03, 2023 from Thomas SchmittGene therapy refers to the introduction of normal foreign genes into target cells to compensate or correct diseases caused by gene defects or abnormalities, so as to achieve the purpose of treatment. Naked DNA usually requires physical methods to enter tissues or cells, and DNA is easily ...
Views: 307 - Gene Structure and Function of Porcine Pseudorabies Virus - by Submitted on Dec 27, 2022 from Thomas SchmittPorcine pseudorabies (PR) is an acute infectious disease of pigs caused by porcine pseudorabies virus (PRV). PRV belongs to the herpesviridae family, the alphaherpesviridae subfamily, and the genus porcine herpesvirus, which is a linear DNA virus. PRV can cause vomiting, high fever and ...
Views: 306 - Gold Nanoparticles in Medicine: A Tiny Marvel with Big Potential - by Submitted on Nov 27, 2023 from Thomas SchmittWith the continuous development of nanotechnology, gold nanoparticles are widely used in the field of medicine. Gold nanoparticles not only have good controllability, biocompatibility, and biosorption, but also have a high degree of stability, and can achieve specific biometrics and functions ...
Views: 299 - How Do Silver Nanoparticles Kill Bacteria? - by Submitted on Jun 28, 2023 from Thomas SchmittSilver nanoparticles (AgNPs) are particles composed of silver atoms, and their particle sizes are usually in the range of 100 nm. Due to their unique physical and chemical properties, silver nanoparticles have been widely used in medical, food, health, consumer, and industrial fields. These ...
Views: 286 - How Do You Test Staphylococcus aureus? - by Submitted on May 28, 2023 from Thomas SchmittStaphylococcus aureus is an important pathogen causing suppurative infection in humans and animals, and it is also one of the common pathogens causing human food poisoning. Staphylococcus aureus is widely distributed in nature, such as air, soil, water, and other environments. This bacteria is ...
Views: 279 - How Does COPD Affect the Lungs?-Animal Models Reveal the Truth - by Submitted on Nov 26, 2024 from Thomas SchmittWhat is COPD? Chronic obstructive pulmonary disease (COPD) is a chronic airway inflammatory disease characterized by progressive airflow limitation. The main symptoms are cough, expectoration, and progressive worsening dyspnea. As of 2017, COPD has become the third-largest cause of death in ...
Views: 109 - How The Liver-Targeted Nano-Drug Delivery System Is Realized - by Submitted on Feb 04, 2021 from Thomas SchmittPhysiological characteristics of the liver The liver is an important organ involved in the processes of digestion, excretion, detoxification and immunity. Liver diseases are common clinical diseases, such as viral hepatitis, cirrhosis and liver cancer, which are extremely harmful to human ...
Views: 470 - How to Calculate the Volume, Mass, and Concentration of Gold Nanoparticle - by Submitted on Jul 28, 2024 from Thomas SchmittGold is a chemically stable metal with a molar mass of 196.96657 g/m and a density of 19.3 g/cm3. It is often used for decoration and money, but its properties change strangely when its size shrinks to the nanometer level. Gold nanoparticles have special physical and chemical properties ...
Views: 187 - How to Know Ultrasound Imaging Contrast Agents in 5 Minutes? - by Submitted on Sep 27, 2022 from Thomas SchmittUltrasound imaging is a well-established clinical imaging technique that provides real-time, quantitative anatomical and physiological information about the human body. It uses high-frequency sound waves to look inside the body, and as ultrasound images are captured in real-time, they can also ...
Views: 311 - Illuminating Possibilities Unveiling the Power of Fluorescent Polystyrene Particles in Biosensing Applications - by Submitted on Jun 28, 2024 from Thomas SchmittA biosensor is a device that measures a biological or chemical reaction by producing a signal that is proportional to the concentration of the analyte in the reaction. Biosensors are used in disease monitoring, drug development, and detection of pollutants, pathogenic microorganisms, and ...
Views: 194 - Illuminating the World of Plasmonic Nanoparticles: Unveiling the Mystery of Plasmons - by Submitted on Jan 23, 2024 from Thomas SchmittSurface plasmon resonance (SPR) and surface-enhanced Raman scattering (SERS) are two key surface plasmon technologies that ultimately enable single-molecule-level chemical and biological sensors. Due to the tremendous progress in solution-based synthesis methods, plasmonic nanoparticles with ...
Views: 245 - Immunological Study on Human Metapneumovirus - by Submitted on Jul 16, 2023 from Thomas SchmittSince Dutch researchers discovered human metapneumovirus (hMPV) in 2001, hMPV and its subtypes have been detected in many countries. hMPV is a respiratory pathogenic virus, which belongs to paramyxovirus, and can express a variety of proteins. Among them, the G, F, and M2 gene proteins are the ...
Views: 305 - Influenza A: Unraveling the Mystery of H1N1 and H3N2 - by Submitted on Apr 03, 2023 from Thomas SchmittInfluenza A viruses, the culprits of respiratory illness in humans, are a complex and multifaceted group of viruses. Among the numerous subtypes of Influenza A, H1N1 and H3N2 with a notorious history of causing seasonal epidemics and pandemics, demand special attention. Influenza A H1N1, also ...
Views: 294 - Introduction of Animal Models in Development of Vaccines - by Submitted on Sep 25, 2024 from Thomas SchmittWhen Jenner discovered the smallpox virus in 1798, scientists realized that animal models could be a powerful tool for studying human infectious diseases. Animal models are commonly used to evaluate various immunological parameters: humoral and cell-mediated immunity, onset and duration of ...
Views: 138 - Introduction of Chitosan as Nano-drug Delivery Carrier - by Submitted on Feb 01, 2023 from Thomas SchmittChitin is the second largest natural polymer after cellulose, and it exists widely in nature, such as shells of crustaceans such as shrimps, crabs, insects, and cell walls of fungi. Although chitin has good biocompatibility and biodegradability, its poor solubility limits its practicality in the ...
Views: 408 - Introduction of Complement Component 5 Receptor - by Submitted on Aug 24, 2022 from Thomas SchmittThe complement system is considered to be a biological effector system composed of a group of thermolabile enzymatically active globulins on the surface of serum, tissue fluid and cell membrane. The membrane attack complex is finally formed by a complex enzymatic cascade reaction, which realizes ...
Views: 302 - Introduction to Measles Virus - by Submitted on Sep 27, 2022 from Thomas SchmittMeasles virus (MV) is the causative agent of measles in children. Measles is a highly contagious infectious disease. According to the World Health Organization, about 20 million children worldwide suffer from measles every year. Measles virus is highly contagious and has high morbidity. In ...
Views: 323 - Is Aspartame Safe? - by Submitted on Aug 18, 2023 from Thomas SchmittAspartame is an artificial dipeptide sweetener, which is synthesized from L-phenylalanine and aspartic acid, and its scientific name is L-aspartic acid-L-phenylalanine methyl ester. It is a white crystalline powder that can be hydrolyzed into aspartic acid and phenylalanine in the body acid, ...
Views: 309 - Legionella Pathogenicity Detection Method - by Submitted on Sep 27, 2022 from Thomas SchmittLegionnaires’ disease (LD) first broke out on a large scale at a military rally in Philadelphia in 1976, killing 34 people. Since then, there have been outbreaks or sporadic transmission of Legionnaires’ disease in the community, in hospitals, and in travel. Legionella is a facultative ...
Views: 291 - Lipid Nanomedicine Delivery In Vivo - by Submitted on Nov 27, 2023 from Thomas SchmittIn the past few decades, the advent of lipid-based nano-delivery systems has brought research in the field of nanomedicines to new heights. Nanocarriers can encapsulate different types of drug molecules and have the advantages of improving drug solubility, extending circulation, achieving ...
Views: 238 - Liposomes for Cosmetics - by Submitted on Aug 17, 2021 from Thomas SchmittLiposomes are spherical vesicles in which their central aqueous section is surrounded by one or more of a bilayer membrane (Lamella) that is frequently enclosed by aquatic environments. These vesicles are formed when amphiphilic lipids confront with aqueous milieu. They can vary in size from 15 ...
Views: 494 - Liposomes for DNA/RNA Delivery - by Submitted on Jun 24, 2021 from Thomas SchmittLiposomes are vesicular structures, and the unique advantages imparted by lipid vesicles are their diverse range of morphologies, compositions, abilities to envelope and protect many types of therapeutic biomolecules, lack of immunogenic response, low cost, and their differential release ...
Views: 383 - Liposomes for DNA/RNA Delivery - by Submitted on Nov 01, 2021 from Thomas SchmittLiposomes are vesicular structures, and the unique advantages imparted by lipid vesicles are their diverse range of morphologies, compositions, abilities to envelope and protect many types of therapeutic biomolecules, lack of immunogenic response, low cost, and their differential release ...
Views: 417 - Mastering Colloidal Gold Handling, Storage, and Applications - by Submitted on Sep 20, 2023 from Thomas SchmittColloidal gold is a certain-size gold particle synthesized by gold ion reduction and polymerization of chloroauric acid (HAuCl4) under the action of reducing agents such as white phosphorus, ascorbic acid, sodium citrate, tannic acid, and so on. Due to electrostatic action, gold particles repel ...
Views: 283 - Mechanism of EBV to Invade Host Cells - by Submitted on Jul 20, 2022 from Thomas SchmittEpstein-Barr virus (EBV) is a kind of γ-herpes virus that is infected with human beings. In 1964, the Epstein team found in Burkittlymphoma (BL) that it consists of a double-chain DNA of 184 KB, mainly through saliva spread. 95%of the world’s people have been infected with EBV, which can be ...
Views: 317 - Mechanism of MDP As a Vaccine Adjuvant Causing Fever - by Submitted on Dec 29, 2019 from Thomas SchmittThe addition of adjuvants to vaccine formulations to enhance the immune response to vaccine antigens by enhancing antigen processing and presentation by antigen presenting cells (APCs) is a common practice for current vaccine formulations. However, since many adjuvants are composed of microbial ...
Views: 474 - Metal-organic Frameworks and Novel Drug-Carrying Systems - by Submitted on Aug 24, 2022 from Thomas SchmittMetal-organic frameworks (MOFs) form long-range ordered geometric structures through the coordination and binding of metal ions and small organic molecules, changing metal elements and small organic molecules, resulting in an ever-expanding family of MOFs. Due to their excellent properties such ...
Views: 329 - Micelle vs Liposome - by Submitted on Jan 23, 2024 from Thomas SchmittMicelles refer to molecularly ordered aggregates that begin to form in large quantities after the surfactant concentration reaches a certain value in an aqueous solution. In micelles, the hydrophobic groups of surfactant molecules aggregate to form the core of the micelle, and the hydrophilic ...
Views: 248 - Microfluidics Revolution: Polystyrene Particles Powering Miniaturized and Automated Immunoassays - by Submitted on May 29, 2024 from Thomas SchmittTraditional immunoassays based on the format of 96-well microtiter plates are widely used in analytical laboratories and have become increasingly automated with the introduction of robotics technology in recent years, thereby enhancing assay throughput. Most clinical analyzers essentially ...
Views: 187 - Microfluidics Revolution: Polystyrene Particles Powering Miniaturized and Automated Immunoassays - by Submitted on Mar 26, 2025 from Thomas SchmittTraditional immunoassays based on the format of 96-well microtiter plates are widely used in analytical laboratories and have become increasingly automated with the introduction of robotics technology in recent years, thereby enhancing assay throughput. Most clinical analyzers essentially ...
Views: 23 - mRNA Nanocarriers - by Submitted on Jun 28, 2024 from Thomas SchmittAs an intermediate carrier, mRNA can transfer the genetic code in DNA to ribosomes for protein expression. It has great potential in vaccines, protein replacement therapy, and gene editing. Compared with traditional small molecule and protein drugs, mRNA-based therapies show some specific ...
Views: 188 - Natural Nanocarriers for Delivery Protein Drug - by Submitted on Sep 20, 2023 from Thomas SchmittProtein accounts for 18-20% of the total mass of the human body and is the main carrier of human life activity. Protein has a range of complex functions in the organism, and many human diseases are closely related to the functional regulation of protein. For example, Parkinson’s disease (PD). It ...
Views: 278 - Neuropilin-1 Promotes SARS-CoV-2 Entry into Host Cells - by Submitted on Apr 01, 2021 from Thomas SchmittThe 2019 Coronavirus Disease (COVID-19) caused by the new coronavirus SARS-CoV-2 is now raging around the world. Existing studies have shown that SARS-CoV-2 infects host cells through the receptor ACE2. In a new study, scientists discovered that neuropilin 1 (NRP1) is a factor that can promote ...
Views: 385 - New Research Reveals the Molecular Mechanism of Cardiolipin - by Submitted on Mar 04, 2021 from Thomas SchmittCardiolipin is a unique phospholipid with a very interesting chemical and specific ultrastructural characteristics. In a research report published in the journal Science Advances in 28 Aug 2020, scientists from Johns Hopkins University and other institutions studied yeast and revealed the ...
Views: 473 - New Research Shows That Shark Antibody-Like Protein Can Neutralize SARS-CoV-2 - by Submitted on Jan 05, 2022 from Thomas SchmittAccording to a new study published in December, small, unique antibody-like proteins called VNARs—from the shark’s immune system—can prevent the virus SARS-CoV-2 that causes COVID-19, its variants, and related coronaviruses from infecting human cells. This work is published in Nature ...
Views: 310 - Nipah Virus Detection Method - by Submitted on Apr 15, 2022 from Thomas SchmittOver the past few decades, there have been multiple outbreaks of viruses causing severe and severe disease around the world, including known and unknown viral pathogens such as SARS-CoV, Ebola, Lassa fever, Marburg virus, Nipah virus, Hendra virus, Rift Valley fever virus and Middle East ...
Views: 349 - Overview of Brucella Abortus - by Submitted on Oct 31, 2022 from Thomas SchmittBrucellosis is a zoonotic infectious disease caused by Brucella, and it is one of the most widespread zoonotic diseases in the world, which brings great losses to the animal husbandry industry. Here, we will outline several aspects about the pathogen, living environment, identification, and ...
Views: 337 - Overview of Monkeypox - by Submitted on Aug 24, 2022 from Thomas SchmittMonkeypox is caused by the monkeypox virus. Monkeypox virus is a virus belonging to the genus Orthopoxvirus of the Poxviridae family. Monkeypox virus has the typical shape of Orthopox virus, with a rounded brick shape or an oval shape and a size of 200-400 nm. The virus is enveloped by a ...
Views: 345 - Overview of Tumor Organoids - by Submitted on Nov 26, 2024 from Thomas SchmittMalignant tumors have become a major challenge in the field of global public health. How to continuously deepen the understanding of the occurrence and development of malignant tumors and continuously optimize the clinical diagnosis and treatment model of tumors is an important issue that needs ...
Views: 101 - Pesticide Residue Testing - by Submitted on Dec 02, 2021 from Thomas SchmittThe development of agricultural industrialization makes the production of agricultural products increasingly dependent on foreign substances such as pesticides, antibiotics and hormones. According to the World Health Organization (WHO), more than 1,000 pesticides are used all over the world. ...
Views: 421 - PLGA Nano Drug Carrier - by Submitted on Apr 25, 2024 from Thomas SchmittPoly(lactic-co-glycolic acid) (PLGA) is a functional polymer organic compound randomly polymerized by lactic acid (PLA) and glycolic acid (PGA). It has been approved by the U.S. Food and Drug Administration It is certified by the Food and Drug Administration (FDA) and is a copolymer material ...
Views: 216 - Polyacrylate Nanoparticles You Don’t Want to Miss - by Submitted on Jul 20, 2022 from Thomas SchmittWhat are polyacrylates nanoparticles? Polyacrylates are an important class of soft, tough and rubbery polymers, which are known for their high transparency, good impact toughness and elasticity. Polyacrylates and their copolymers are one of the polymeric nanoparticles (NPs). Polymeric ...
Views: 263 - Potential Small-molecule Drug Targets for COVID-19 - by Submitted on Mar 04, 2021 from Thomas SchmittViruses must enter the host cell to replicate in order to function. Therefore, antiviral drugs can be designed for a series of targets in the process of virus interaction with cell receptors, gene replication, transcription and translation when the virus invades host cells and completes its life ...
Views: 415 - Progress in the Development of Targeted Anti-Tumor Antibody-Drug Conjugates - by Submitted on Mar 27, 2024 from Thomas SchmittAntibody-drug conjugates (ADCs) are conjugated products of monoclonal antibodies (mAbs) and cytotoxic small molecules. In tumor treatment, although monoclonal antibodies have good targeting properties, most of them target extracellular or cell surface antigens, have weak anti-tumor activity, ...
Views: 259 - Quantum Dots Technology in Fluorescent Labeling - by Submitted on Jul 23, 2021 from Thomas SchmittLiposomes are vesicular structures, and the unique advantages imparted by lipid vesicles are their diverse range of morphologies, compositions, abilities to envelope and protect many types of therapeutic biomolecules, lack of immunogenic response, low cost, and their differential release ...
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