Intermittent fasting (IF) has been studied for its potential benefits on various aspects of health and cognition, including neuroplasticity and neurogenesis.

Several studies have suggested that intermittent fasting can promote neuroplasticity, which is the brain's ability to adapt and reorganize itself in response to experiences. One study published in the journal Nature Communications in 2020 found that intermittent fasting in mice increased the number of new neurons in the hippocampus, a region of the brain important for learning and memory.

Another study published in the journal Aging in 2021 found that intermittent fasting in rats improved cognitive function and increased levels of proteins involved in neuroplasticity.

Furthermore, intermittent fasting has also been shown to increase levels of brain-derived neurotrophic factor (BDNF), a protein that promotes the growth and survival of neurons, which may contribute to increased neuroplasticity and neurogenesis.

Overall, while more research is needed, the existing studies suggest that intermittent fasting may have positive effects on neuroplasticity and neurogenesis. However, it is important to note that the effects of intermittent fasting may vary depending on individual factors such as age, sex, and overall health status.


BDNF can potentially help with recovery from traumatic brain injury (TBI). Studies have shown that BDNF is involved in many processes that are important for brain repair and recovery after injury. For example, BDNF has been shown to promote the growth and survival of neurons, stimulate the formation of new blood vessels, and enhance the production of proteins that are involved in cell repair and regeneration.

In addition, some studies have suggested that increasing BDNF levels after TBI may improve outcomes. For example, a study published in the journal Neuropsychopharmacology in 2017 found that treatment with a BDNF-mimetic compound improved cognitive function and reduced brain inflammation in rats with TBI.

It's important to note that the effects of BDNF on TBI may vary depending on the severity of the injury and other individual factors. Therefore, it's important to talk to your healthcare provider about the best course of treatment for your specific situation.

BDNF and Cognitive Impairment Spasticity and Hemipaesis

Increasing BDNF levels may also potentially help with cognitive impairment and memory loss, even if they are related to a past traumatic brain injury (TBI). As I mentioned earlier, BDNF is involved in many processes that are important for brain health and function, including neuroplasticity and neurogenesis, which are crucial for learning, memory, and cognitive function.

Also, there is some evidence to suggest that increasing BDNF levels and promoting neuroplasticity and neurogenesis may help with issues related to TBI, such as spasticity and hemiparesis. 

For example, a study published in the journal Brain Research in 2013 found that increasing BDNF levels through treadmill training improved motor function in rats with TBI.

Similarly, a study published in the journal Neural Regeneration Research in 2015 found that treatment with a BDNF-mimetic compound improved motor function and reduced spasticity in rats with spinal cord injury.

In humans, a study published in the journal Neurorehabilitation and Neural Repair in 2014 found that intensive exercise training increased BDNF levels and improved gait speed and balance in people with chronic stroke.

While these studies are promising, it's important to note that the effects of BDNF on spasticity and hemiparesis may vary depending on individual factors and the severity of the injury. Therefore, it's important to work with your healthcare provider to determine the best course of treatment for your specific situation.

In addition to increasing BDNF levels, there are also other treatments and therapies that may be helpful for spasticity and hemiparesis, such as physical therapy, occupational therapy, and medications.

Author's Bio: 

Read more from the Author Leon Edward at his website and blog or book co written with Dr Anum Khan, "Concussion, Traumatic Brain Injury, Mild TBI Ultimate Rehabilitation Guide, Click Here

About the book's co-authors Leon Edward and Dr. Anum Khan

For Leon Edward, the past 35 years since the tbi left one lingering desire: the need to give something back, a way to provide something meaningful for the families and loved ones of patients who now, or in the future, will face the same painful disruption of their lives and the same long journey he had to undertake such a long time ago.“I want to be clear in the introduction that I am not a health professional as my co author Dr. Khan , but rather an engineer that has had a tbi" - Leon Edward

This book was written by one deeply caring brother for his brothers and sisters suffering the same or even a worse fate after surviving traumatic brain injuries – and with deep admiration and appreciation for their families and caretakers who will help to guide them.

For Leon it has become an ingrained part of his existence to help others enjoy life after suffering serious injuries, even if it only means that he can help others who are disabled or living alone with words of hope, encouragement of inspiration.

Dr. Anum Khan enjoys crafting health content that genuinely helps the readers in a practical and insightful way. She believes that a healthy life is everyone’s true right, and it must be taught in an easy and effective manner using the most authentic information and relatable voice.

Their book comes with the same intent: To help sufferers, families and professionals learn more about TBI with a holistic approach, and to equip them with all the knowledge they will need on this journey.

Click Here for a paperback or ebook or to read free with kindle unlimited try kindle unlimited free, click here

The author Leon Edward, a TBI survivor who has overcome much and succeeded in an engineering and managerial career plus a personal growth-focused career as an author afterward.

After the gunshot to the head, he had a remarkable team to rehab his physical and mental health with amazing work on improving cognitive abilities.

Following the remarkable recovery, during his mechanical engineering studies, graduate study, and two decade-plus successful career, a laser focus and optimizing, prioritizing schedule and work tasks for most efficient productivity while also getting more done in less time has been essential. In studying and applying top research and experiencing the benefits of audio that optimize brainwave entrainment as well as cognitive benefits seen in brainwave meditation.

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